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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLNS1A
All Species:
19.09
Human Site:
Y152
Identified Species:
30
UniProt:
P54105
Number Species:
14
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54105
NP_001284.1
237
26215
Y152
D
D
Y
D
G
E
E
Y
D
V
E
A
H
E
Q
Chimpanzee
Pan troglodytes
XP_001175048
222
24569
E142
L
H
P
D
P
E
D
E
D
S
D
D
Y
D
G
Rhesus Macaque
Macaca mulatta
XP_001088333
203
22330
H123
E
E
Y
D
V
E
A
H
E
Q
G
Q
G
D
I
Dog
Lupus familis
XP_535567
226
24585
H146
E
E
Y
D
V
E
A
H
E
Q
G
Q
G
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61189
236
26003
Y151
D
D
Y
D
G
E
E
Y
D
V
E
A
H
E
Q
Rat
Rattus norvegicus
Q04753
236
26074
Y151
D
D
Y
D
G
E
E
Y
D
V
E
A
H
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519221
278
30242
D162
D
Y
E
G
G
E
Y
D
V
E
A
H
E
R
G
Chicken
Gallus gallus
XP_423253
238
26615
Y153
N
D
Y
E
G
D
E
Y
D
V
E
A
R
E
L
Frog
Xenopus laevis
P54106
241
26428
Y156
D
D
Y
E
G
D
E
Y
D
V
E
A
H
E
Q
Zebra Danio
Brachydanio rerio
NP_571499
249
27316
E165
G
E
E
Y
D
V
E
E
A
E
Q
E
Q
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611237
215
23724
E135
E
Q
F
G
E
V
T
E
C
W
L
M
P
E
D
Honey Bee
Apis mellifera
XP_624081
207
23224
M127
N
T
N
N
L
E
A
M
F
Q
A
M
N
Q
C
Nematode Worm
Caenorhab. elegans
NP_001021287
205
22895
Y125
K
D
S
L
S
Q
I
Y
H
Q
I
A
V
G
Q
Sea Urchin
Strong. purpuratus
XP_001194575
165
18108
D85
E
I
R
L
V
P
Q
D
K
T
M
L
Q
S
M
Poplar Tree
Populus trichocarpa
XP_002318279
231
25740
P151
C
E
C
A
E
L
N
P
E
P
V
E
D
N
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
85.6
82.2
N.A.
90.3
90.3
N.A.
40.6
82.3
72.1
68.2
N.A.
20.2
40
29.9
24.4
Protein Similarity:
100
93.2
85.6
85.2
N.A.
94.9
94.9
N.A.
53.2
90.3
82.5
80.3
N.A.
37.5
56.5
45.5
40.9
P-Site Identity:
100
20
20
20
N.A.
100
100
N.A.
20
66.6
86.6
13.3
N.A.
6.6
6.6
26.6
0
P-Site Similarity:
100
46.6
53.3
53.3
N.A.
100
100
N.A.
20
86.6
100
26.6
N.A.
20
33.3
33.3
13.3
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
20
0
7
0
14
40
0
7
0
% A
% Cys:
7
0
7
0
0
0
0
0
7
0
0
0
0
0
7
% C
% Asp:
34
40
0
40
7
14
7
14
40
0
7
7
7
20
7
% D
% Glu:
27
27
14
14
14
54
40
20
20
14
34
14
7
40
7
% E
% Phe:
0
0
7
0
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
7
0
0
14
40
0
0
0
0
0
14
0
14
7
14
% G
% His:
0
7
0
0
0
0
0
14
7
0
0
7
27
0
0
% H
% Ile:
0
7
0
0
0
0
7
0
0
0
7
0
0
0
14
% I
% Lys:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% K
% Leu:
7
0
0
14
7
7
0
0
0
0
7
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
7
0
0
7
14
0
0
7
% M
% Asn:
14
0
7
7
0
0
7
0
0
0
0
0
7
7
0
% N
% Pro:
0
0
7
0
7
7
0
7
0
7
0
0
7
0
0
% P
% Gln:
0
7
0
0
0
7
7
0
0
27
7
14
14
7
40
% Q
% Arg:
0
0
7
0
0
0
0
0
0
0
0
0
7
7
0
% R
% Ser:
0
0
7
0
7
0
0
0
0
7
0
0
0
7
0
% S
% Thr:
0
7
0
0
0
0
7
0
0
7
0
0
0
0
0
% T
% Val:
0
0
0
0
20
14
0
0
7
34
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
7
47
7
0
0
7
40
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _